Summary: The highly lethal brain cancer glioblastoma GOLD STANDARD CASEIN CHOCOLATE (GBM) poses a daunting challenge because the blood-brain barrier renders potentially druggable amplified or mutated oncoproteins relatively inaccessible.Here, we identify sphingomyelin phosphodiesterase 1 (SMPD1), an enzyme that regulates the conversion of sphingomy
Humans use natural products to treat disease; similarly, some insects use natural products produced by Actinobacteria to combat infectious pathogens.Honey bees, Apis mellifera, are ecologically and economically important for their critical role as plant pollinators and are host to diverse and potentially virulent pathogens that threaten hive health
Abstract Purpose To evaluate the comprehensiveness and navigation ease of online content from Web sites of U.S.academic ophthalmology departments.Design Cross-sectional analysis of 117 U.S.academic ophthalmology department Web sites from October 1 to October 31, 2017.Methods Data were obtained on various categories, including: clinical access and s
Cardiac amyloidosis Room Spray is a rare, debilitating, and usually fatal disease increasingly recognized in clinical practice despite patients presenting with non-specific symptoms of cardiomyopathy.The current standard of care (SoC) focuses on preventing further amyloid formation and deposition, either with anti-plasma cell dyscrasia (anti-PCD) t
The solar energy is a source of energy that is abundant in Malaysia and can be easily harvested.However, because of the rotation of the Earth about its axis, it is impossible to harvest the solar energy to the maximum capacity if Anti-Perspirant the solar thermal collector is placed fix to a certain angle.In this research, a solar thermal dish with